What is BPC-157? A Research Overview

BPC-157 (Body Protection Compound) is a synthetic pentadecapeptide — a chain of 15 amino acids — derived from a protein found in gastric juice. Its sequence is: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val.

Research Background

BPC-157 has been studied in laboratory and animal model settings since the early 1990s. The compound was first described in the context of gastric cytoprotection research and has since been studied across a range of biological models.

Key Research Areas

• Tendon and ligament fibroblast models — cell proliferation and migration studies
• Gastrointestinal mucosa — protective effects in rat models of gastric ulceration
• Neurological models — dopaminergic and serotonergic pathway studies in animal models
• Angiogenesis — vascular endothelial growth factor (VEGF) pathway studies in wound healing models
• Systemic administration studies — intraperitoneal and subcutaneous routes in rodent models

Supply and Storage

Research-grade BPC-157 is typically supplied as a lyophilized (freeze-dried) white powder in sealed, sterile vials. Purity should be verified by HPLC at ≥98%, with sequence identity confirmed by mass spectrometry. Lyophilized BPC-157 is stable at room temperature for up to 24 months. Once reconstituted in bacteriostatic water, it should be stored at −20°C and used within 30 days.

What to Look for in a Supplier

• HPLC purity ≥98% from an independent third-party laboratory
• Mass spectrometry identity confirmation (sequence verification)
• Lot-specific COA — not a generic company certificate
• Lot number on the vial label matching the COA